Evidence base

Studies on Fisetin

Auto-loaded from PubMed — grouped by outcome. Each entry links to the original source.

1,572 studies total·Last updated: May 27, 2026Open on PubMed

Longevity & aging · 113

Open on PubMed
  1. 01
    Computational exploration of squalene analog 4,4'diapophytofluene as a potential anti-aging phytotherapeutic
    Dutta M, Hazra A, Mandal Biswas S · Comput Biol Chem · 2026
  2. 02
    T-Cell Immunosenescence in Systemic Lupus Erythematosus: Molecular Mechanisms and Therapeutic Perspectives
    Zhou S, Jian L, Chen H et al. · Clin Rev Allergy Immunol · 2026
  3. 03
    Lipid- and Polymer-Based Nanoscale Delivery of Anti-Aging Phytochemicals
    Gross S, Vogtlander C, Lewis C et al. · Wiley Interdiscip Rev Nanomed Nanobiotechnol · 2026
  4. 04
    Fisetin Supplementation Attenuates Premature Vascular Aging Induced by Doxorubicin via Suppression of Cellular Senescence and Mitochondrial Oxidative Stress
    Darrah MA, Mahoney SA, Venkatasubramanian R et al. · Aging Cell · 2026
  5. 05
    Senolytic Treatment With Fisetin Reverses Age-Related Endothelial Dysfunction Partially Mediated by SASP Factor CXCL12
    Mahoney SA, Mazan-Mamczarz K, Tsitsipatis D et al. · Aging Cell · 2026
  6. 06
    Exploring the Senotherapeutic Potential of Polyphenols in Aging and Disease: A Literature Review
    Braučič Mitrovic L, Semen KO · Int J Mol Sci · 2026
  7. 07
    Senolytic reduction of senescent cells mitigates atrial arrhythmia vulnerability in aging rabbits
    Sengun E, Zhou L, Kelsey M et al. · Heart Rhythm · 2026
  8. 08
    Celastrol Targets Hsc70-Bim Interaction as a Novel Senolytic to Extend Lifespan and Mitigate Organ Fibrosis
    Xu W, Chen H, Gong H et al. · Phytother Res · 2026
  9. 09
    Evaluating senescence-targeted approaches in Alzheimer's Disease: What we know and what lies ahead
    Doshi PP, Desale SH, Khutale AA et al. · Ageing Res Rev · 2026
  10. 10
    Fisetin: a multitarget flavonol bridging oxidative stress, inflammation, aging, and cancer
    Chahal SK, Kabra A, Saeedan AS et al. · Naunyn Schmiedebergs Arch Pharmacol · 2026
  11. 11
    Natural senotherapeutics in respiratory health: Addressing cellular senescence, inflammaging, and immunosenescence in the aging lung
    Juan ME, Verdaguer E, Prohens R et al. · Eur J Pharmacol · 2026
  12. 12
    Targeting senescent EGR1(+) B cells enhances immunotherapy efficacy in esophageal squamous cell carcinoma
    Zhou P, Zhang Y, Zhang H et al. · Cell Rep Med · 2026
  13. 13
    Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically diverse Caenorhabditis nematodes
    Banse SA, Sedore CA, Coleman-Hulbert A et al. · Elife · 2025
  14. 14
    Senolytics as Modulators of Critical Signaling Pathways: a Promising Strategy to Combat Brain Aging and Neurodegenerative Disorders
    Singh I, Singh AK · Mol Neurobiol · 2025
  15. 15
    Endothelial senescent-cell-specific clearance alleviates metabolic dysfunction in obese mice
    Suda M, Chaib S, Langhi Prata LGP et al. · Cell Metab · 2025
  16. 16
    Erythropoietin as a multifaceted antiaging agent: Mechanisms and clinical potential
    Wang T, Tang Y, Xiao Y · J Pharmacol Exp Ther · 2025
  17. 17
    Molecular Mechanisms Behind Organ-Related Aging and Regulatory Effects of Natural Therapeutics
    Abaidullah R, Ali S, Summer M et al. · Cell Biochem Biophys · 2025
  18. 18
    Orchestration of Skin Pathology in Cutaneous Lupus Erythematosus by HLA Class I Down-Regulated Senescent Epidermal Basal Cells
    Yamamoto S, Saito Y, Sato T et al. · Arthritis Rheumatol · 2025
  19. 19
    Vascular Niches Are the Primary Hotspots in Cardiac Aging
    Rodriguez Morales D, Larcher V, Ruz Jurado M et al. · Circ Res · 2025
  20. 20
    Evaluation of the association between sex-linked genes and treatment response in lung cancer
    Kinsella A, Prina-Mello A, Marignol L · Radiother Oncol · 2025
  21. 21
    Preventive Effect of Fisetin on Follicular Granulosa Cells Senescence via Attenuating Oxidative Stress and Upregulating the Wnt/β-Catenin Signaling Pathway
    Dong J, Yang Z, Yuan Q et al. · Cells · 2025
  22. 22
    Heterogeneity of Cellular Senescence, Senotyping, and Targeting by Senolytics and Senomorphics in Lung Diseases
    Ozdemir SA, Faizan MI, Kaur G et al. · Int J Mol Sci · 2025
  23. 23
    Premature renal epithelial cell senescence promoted by LXN/Rps3/p53 signaling pathway activation increases calcium oxalate crystal deposition by altering macrophage polarization
    Chu M, Jiang S, Xue J et al. · Front Immunol · 2025
  24. 24
    Discovery of dietary beneficial compounds for healthy aging: From worm to human
    Ye X, Wang H, Han Y et al. · Food Res Int · 2025
  25. 25
    Targeting Cellular Senescence for Healthy Aging: Advances in Senolytics and Senomorphics
    Alum EU, Izah SC, Uti DE et al. · Drug Des Devel Ther · 2025