Evidence base

Studies on Green Tea

Auto-loaded from PubMed — grouped by outcome. Each entry links to the original source.

18,486 studies total·Last updated: June 4, 2026Open on PubMed

Longevity & aging · 260

Open on PubMed
  1. 01
    Early-life redox perturbation programs intergenerational redox vulnerability through DAF-16/FOXO and SKN-1/Nrf2 signaling in Caenorhabditis elegans
    Liang J, Zhao Y, Xie Y et al. · Redox Biol · 2026
  2. 02
    Age-related changes in salivary gland-associated oral immune markers and effects of epigallocatechin gallate in male C57BL/6J mice
    Uemura I, Takahashi-Suzuki N, Sano A et al. · Arch Oral Biol · 2026
  3. 03
    Dietary Polyphenols in Aging: A Systems-Level Perspective on Mitochondrial Quality Control and Microbiome Interactions
    Yılmaz A, Park HJ, Ahn EM et al. · Int J Mol Sci · 2026
  4. 04
    [Effects of Japanese Green Tea on the Brain: Prevention of Aging]
    Unno K · Brain Nerve · 2026
  5. 05
    Dietary Antioxidants, Polyphenols, and Vascular Health: Insights From Ultrasound Measurement of Carotid Intima-Media Thickness and Their Association With Cognitive Function in Aging and Neurodegenerative Diseases
    Wang L, Luo Z, Liu D · Phytother Res · 2026
  6. 06
    Treatment of age-related decreases in GTP levels restores endocytosis and autophagy
    Santana RA, McWhirt JM, Brewer GJ · Geroscience · 2026
  7. 07
    Epigallocatechin gallate mitigates oxidative stress-induced transient senescence and injury by preserving mitochondrial integrity and restoring redox-inflammatory homeostasis in murine macrophages
    Kumar R, Goel A, Sharma R et al. · Biogerontology · 2026
  8. 08
    A dual-delivery nanotherapeutic strategy using chitosan-epigallocatechin-3-gallate nanoparticles encapsulated in exosomes: A novel approach to combat brain aging
    Salem NA, Mowaad NA, Elgohary R et al. · Int J Biol Macromol · 2026
  9. 09
    Natural senotherapeutics in respiratory health: Addressing cellular senescence, inflammaging, and immunosenescence in the aging lung
    Juan ME, Verdaguer E, Prohens R et al. · Eur J Pharmacol · 2026
  10. 10
    Dietary Theogallin Enhances Cognitive Function and Neuronal Activation via Immediate-Early Gene Activation in Aged Mice
    Lee K, Otsuka Y, Kumazoe M et al. · J Agric Food Chem · 2026
  11. 11
    Association between nutritional status and sleep quality in older adults: an update
    Xu X, Wang M · Curr Opin Clin Nutr Metab Care · 2026
  12. 12
    Matcha intake enhances systemic oxidative stress resistance and activates detoxification pathways in Drosophila melanogaster
    Tsuda M · Biosci Biotechnol Biochem · 2025
  13. 13
    Dietary factors and MRI biomarkers of brain ageing in general populations: a comprehensive systematic review
    Kim MK, Kwon BJ, Kim YM et al. · Nutr Res Rev · 2025SR
  14. 14
    Preventive Effect of Epigallocatechin-3-Gallate on Postoperative Cognitive Dysfunction in Aged Rats via Modulation of Microglial Differentiation: An Experimental Animal Study
    Hong SW, Piao L, Cho EH et al. · Int J Mol Sci · 2025
  15. 15
    Serum Galectin-9 and Decorin in relation to brain aging and the green-Mediterranean diet: A secondary analysis of the DIRECT PLUS randomized trial
    Pachter D, Yaskolka Meir A, Kaplan A et al. · Clin Nutr · 2025RCT
  16. 16
    Effect and Mechanism of Whey Protein Isolate-Epigallocatechin Gallate Non-Covalent Complex on Skeletal Muscle Attenuation in Aging Mice
    Yang Y, Liu Y, Chen C et al. · J Food Sci · 2025
  17. 17
    Influence of a diet with potential geroprotectors on blood biochemistry and aging-associated markers in domestic cats: a pilot study
    Protopopov VA, Sekunov AV, Toropova TV et al. · Biogerontology · 2025
  18. 18
    Increasing Life Expectancy with Plant Polyphenols: Lessons from the Mediterranean and Japanese Diets
    Fiore M, Tonchev AB, Pancheva RZ et al. · Molecules · 2025
  19. 19
    Epigallocatechin-3-gallate mitigates postovulatory oocyte aging by reducing oxidative stress and promoting embryonic development
    Gong L, Fan RN, Peng J et al. · Reproduction · 2025
  20. 20
    Undescribed Phenylpropanoid-Substituted Ester-Type Catechins from Green Tea Exert Antiaging Effects in Caenorhabditis elegans via Activating DAF-16, HSF-1, and Heat Shock Proteins
    Yang Z, Zhang YX, Song N et al. · J Agric Food Chem · 2025
  21. 21
    Dietary flavonoid actions on senescence, aging, and applications for health
    Watkins BA, Mitchell AE, Shin AC et al. · J Nutr Biochem · 2025
  22. 22
    Dietary associations with reduced epigenetic age: a secondary data analysis of the methylation diet and lifestyle study
    Villanueva JL, Vita AA, Zwickey H et al. · Aging (Albany NY) · 2025RCT
  23. 23
    Green Tea Mitigates the Hallmarks of Aging and Age-Related Multisystem Deterioration
    Yilmaz Y · Aging Dis · 2025
  24. 24
    Effects of green tea catechins and exercise on age-related muscle atrophy and satellite cell functions in a mouse model of sarcopenia
    Matsuzaki R, Matsuoka T, Nakanishi K et al. · Exp Gerontol · 2025
  25. 25
    EGCG Mitigates Apoptosis of Lens Epithelial Cells in Age-Related Cataract via the PAK1/Cleaved Caspase-3 Pathway
    Zhang Y, Su D, Sun Z et al. · Curr Mol Med · 2025

Metabolic health · 497

Open on PubMed
  1. 01
    Ferroptosis targeted metal-phenolic nanocomposite hydrogel for immune microenvironment guided regeneration of diabetic bone defects
    Hao Y, Zhang Y, Sun J et al. · Biomaterials · 2026
  2. 02
    A Straw-Reinforced-Clay-Inspired Composite Hydrogel Promotes Diabetic Bone Regeneration via Driving the Immune-Osteogenic Cascade to Remodel Mitochondrial Homeostasis
    Li Y, Cui Z, Liao H et al. · ACS Nano · 2026
  3. 03
    Dual-responsive antibacterial hydrogels encapsulating Periodontal Ligament Stem Cells for macrophage reprogramming and diabetic wound healing
    Wang K, Zhuo S, Zhao Y et al. · J Control Release · 2026
  4. 04
    MOF-reinforced NIR-responsive composite hydrogel with photothermal antibacterial and antioxidant activities for diabetic wound healing
    Zhang Z, Wang Y, Sun B et al. · Biomater Sci · 2026
  5. 05
    Use of Small Organic Molecules to Improve Pancreatic Beta Cell Resilience to IAPP-Induced Proteotoxic Stress
    Valshon K, Kondrot K, Uehara H et al. · Int J Mol Sci · 2026
  6. 06
    Green Tea Catechin Plus Inulin Improves Insulin Resistance Without Reducing Visceral Fat and Shows Exploratory Gut Microbiota Signals in Adults with Visceral Obesity: A Double-Blind Randomized Controlled Trial
    Iino C, Mikami K, Furusawa K et al. · Nutrients · 2026RCT
  7. 07
    Epigallocatechin gallate prevents and alleviates type 2 diabetes mellitus (T2DM) through gut microbiota and multi-organ interactions in Wistar healthy rats and GK T2DM rats
    Zeng H, Liu C, Wan L et al. · J Adv Res · 2026
  8. 08
    An EGCG-enhanced pH/ROS dual-responsive hyaluronic acid hydrogel loaded with ginseng-derived exosomes for diabetic oral ulcers treatment
    Li D, Yu Y, Fan R et al. · Int J Biol Macromol · 2026
  9. 09
    Screening and predictive analysis of common regulatory genes in diabetes and rectal cancer: transcriptional and drug modulation mechanisms
    Wu S, Huo H, Liu Y et al. · Eur J Med Res · 2025
  10. 10
    The Association Between Green Tea Intake and Metabolic Syndrome: A Systematic Review and Meta-analysis of Randomized Controlled Trials
    Ghoflchi S, Mohammadi H, Teimouri M et al. · Clin Ther · 2025SR
  11. 11
    Herbal Approaches to Diabetes Management: Pharmacological Mechanisms and Omics-Driven Discoveries
    Roy D, Ghosh M, Rangra NK · Phytother Res · 2025
  12. 12
    Enhanced skin regeneration in diabetic wounds using collagen-hyaluronic acid scaffold incorporated with epigallocatechin gallate: a multifactorial healing approach
    Alhasani RH · Histochem Cell Biol · 2025
  13. 13
    The effects of a newly developed beverage powder supplement on anthropometric measures, body composition, metabolic syndrome components, and appetite in obese or overweight adults: a protocol for a randomized clinical trial study
    Asghari P, Afshari A, Sadeghi T et al. · Trials · 2025
  14. 14
    ROS/Glucose-Dissociable EGCG-Coated Oxygen-Supplying Nanocomposite Hydrogel for Diabetic Wound Therapy
    Sun S, Zhu R, Du J et al. · Int J Nanomedicine · 2025
  15. 15
    Green tea containing inulin and catechins ameliorates high-fat diet-induced metabolic dysfunction-associated fatty liver disease in mice
    Lee YH, Huang CC, Lin HL et al. · Int J Med Sci · 2025
  16. 16
    Effect of Epigallocatechin Gallate on Glycemic Index: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
    Saadh MJ, Gataa IS, Hussam AS et al. · Clin Ther · 2025Meta
  17. 17
    Matcha Green Tea Improves Cafeteria-Diet-Induced NAFLD by Modulating the Gut Microbiota in Rats
    Chong HC, Tang ST, Tseng YC et al. · Nutrients · 2025
  18. 18
    A dual-network supramolecular hydrogel dressing encapsulating Cu/EGCG nanoenzyme and glucose oxidase for closed cascade catalytic therapy of diabetic wounds
    Yu W, Liu Z, Mao S et al. · J Mater Chem B · 2025
  19. 19
    Alcohol and Tea Consumption in Relation to Liver Cancer Risk by Diabetes Status: A Prospective Cohort Study of 0.5 Million Chinese Adults
    Feng X, Li R, Yan M et al. · Nutrients · 2025
  20. 20
    Design and evaluation of sodium alginate-based hydrogel containing green tea for the treatment of diabetic ulcers in rat model
    Norouzi P, Rezaei Kolarijani N, Mahheidari N et al. · J Biomater Appl · 2025
  21. 21
    (-)-Epigallocatechin-3-gallate and chlorogenic acid in combination with vitamin D as a therapeutic approach for letrozole-induced polycystic ovary syndrome (PCOS) rats: Biochemical and hormonal modulation
    Siddiqui S, Ahmad R, Aziz T et al. · J Steroid Biochem Mol Biol · 2025
  22. 22
    Mechanism of Huoshan large-leaf yellow tea in treatment of diabetic cognitive dysfunction based on bioinformatics and network pharmacology
    Li R, Lou Q, Zhu Y et al. · Phytomedicine · 2025
  23. 23
    Use of herbal products by diabetic patients in coping with health problems: a cross-sectional study from Turkey
    Doğar E, Akbayram HT, Büyükdereli Atadağ Y · Intern Emerg Med · 2025
  24. 24
    The Impact of Tea Consumption on Prediabetes Regression and Progression: A Prospective Cohort Study
    Li T, Rayner CK, Horowitz M et al. · Nutrients · 2025
  25. 25
    A review on mechanistic actions of epigallocatechin-3-gallate in targeting the ominous octet of type 2 diabetes mellitus
    Wong CN, Lim YM, Liew KB et al. · J Integr Med · 2025

Cardiovascular · 745

Open on PubMed
  1. 01
    EGCG-loaded nanoparticles attenuate post-SAH white matter injury by targeting HO-1/S100A10 to suppress oxidative stress-induced reactive astrocytes
    Lang D, Zheng Y, Zhang J et al. · Redox Rep · 2026
  2. 02
    Redox-responsive drug delivery nanoparticles with integrated capabilities of ROS scavenging, lipid removal and anti-inflammation
    Zhou L, Chen T, Wang K et al. · Biomater Adv · 2026
  3. 03
    Evaluation of Neonatal Cardiotoxicity Following Maternal Green Tea Extract Consumption During Pregnancy: An Experimental Rat Study on the Cytochrome c/Caspase-9/Caspase-3 Pathway
    Sayın O, Çalım Sİ, Çigel A et al. · Medicina (Kaunas) · 2026
  4. 04
    A Novel circRERE/miR-27a-3p/Caspase9 Signaling Axis Promotes Cardiomyocyte Apoptosis in Ischemic Myocardium: Insights from Epigallocatechin Gallate-Primed Exosomes
    Li H, Wang M, Li Y et al. · Cells · 2026
  5. 05
    A carrier-free nanomedicine targeting vascular remodeling and oxidative stress for enhanced pulmonary arterial hypertension therapy
    Zhou J, Yang Y, Zou H et al. · J Colloid Interface Sci · 2026
  6. 06
    Effect of Green Tea Kombucha Within an Energy-Restricted Diet on Cardiometabolic Risk Markers in Individuals With Excess Body Weight: A Randomized Controlled Trial
    Bonifácio DB, Fraiz GM, Lacerda UV et al. · J Food Sci · 2026RCT
  7. 07
    Epigallocatechin gallate ameliorates brain injuries after intracerebral hemorrhage by inhibiting ferroptosis through upregulation of Nrf2-Keap1 pathway
    Zhou SY, Guo ZN, Sun YY et al. · Brain Res Bull · 2026
  8. 08
    Pharmacological effects and molecular targets of L-theanine in cardiovascular diseases and comorbidities
    García-Niño WR, Zúñiga-Muñoz AM, Maldonado-Macías XP · Eur J Pharmacol · 2026
  9. 09
    ROS-responsive Prussian blue nanoplatform for synergistic myocardial ischemia/reperfusion injury therapy via EGCG delivery and DJ-1 pathway regulation
    Zhang J, He Y, Wu Y et al. · Int J Pharm · 2026
  10. 10
    Therapeutic Potential and Mechanistic Pathways of Plant-Based Supplements and Exercise Training in Blood Pressure Management: An Evidence-Based Review and Research Agenda
    Taati B, Badicu G, Vveinhardt J · Nutrients · 2026
  11. 11
    Epigallocatechin Gallate, Resveratrol, and Triptolide Are Candidate Natural Drugs Which Target Huh Proteins in Atherosclerosis Pathogenesis
    Zhu X, Nie Y, Zhang H et al. · Chem Biol Drug Des · 2026
  12. 12
    Targeting PKC/NF-κB/NLRP3-driven NcRNA neuroinflammatory crosstalk by condensed tannins in global cerebral ischemia
    Pachauri PK, Panda SP · Inflammopharmacology · 2026
  13. 13
    Self-adaptive covalent coating for vascular stents: Coordinated coagulation-inflammation regulation to support re-endothelialization for atherosclerosis control
    Wang Y, Zhu Q, Chen Z et al. · Biomaterials · 2026
  14. 14
    Catechins for use in cardiovascular disease: Molecular mechanisms and contemporary bioassays
    Keller AC, Lanaspa MA · J Pharm Biomed Anal · 2026
  15. 15
    Causal relationship between consumption of different tea types and the risk of stroke: A two-sample Mendelian randomization analysis
    Jiang X, Lin Q, Gao W et al. · Medicine (Baltimore) · 2026
  16. 16
    Inhibition of ADAMTS1 and ATP citrate lyase attenuates connexin-43 degradation and HFrEF
    Zheng Y, Tyagi S · Can J Physiol Pharmacol · 2026
  17. 17
    Mediterranean-DASH Intervention for Neurodegenerative Delay Diet to Improve Cognitive Function in Mild Stroke Patients: Rationale and Design of Two Replicate, Pilot Randomized Control Trials
    Lin Q, Chen H, Shen J et al. · Cerebrovasc Dis · 2026
  18. 18
    Phytoconstituents-mediated Targeting of Ferroptosis for the Treatment of Cardiovascular Disease
    Gupta P, Sharma A, Sachin et al. · Curr Cardiol Rev · 2026
  19. 19
    Metal-phenolic networks assisted construction of multi-layered endothelium-mimetic polyelectrolyte coating with nitric oxide generation and glycocalyx functionalization
    Chen C, Zhang C, Yu T et al. · Biomaterials · 2026
  20. 20
    Oral Exposure To SiO(2) Nanoparticles Promotes Foam Cell Areas in Aortic Sinus of ApoE-/- Mice and Epigallocatechin Gallate Attenuates the Effects via Metabolic Restoration
    Zhao X, Li K, Liu Q et al. · Cardiovasc Toxicol · 2025
  21. 21
    Effect of green tea supplementation on blood pressure in adults: a GRADE-assessed systematic review and dose-response meta-analysis of randomised controlled trials
    Rezaei M, Akhavan N, Fathi F et al. · Blood Press · 2025Meta
  22. 22
    Association of tea consumption with all-cause/cardiovascular disease mortality in the chronic kidney disease population: an assessment of participation in the national cohort
    Li J, Chen XL, Ou-Yang XL et al. · Ren Fail · 2025
  23. 23
    Evaluation of wound regeneration potential of nano-phytoextracts loaded carboxymethyl chitosan scaffolds for diabetic foot ulcer
    Radhakrishnan V, Sabu L, Somayaji P et al. · Sci Rep · 2025
  24. 24
    Unveiling the influence of polyphenols on histone modifications in human diseases
    Wu Q, Xiao C, Ouyang B et al. · Phytomedicine · 2025
  25. 25
    Epigallocatechin Gallate as a Molecular Therapeutic in Heart Failure and Cardio-Oncology: Mechanistic Pathways and Translational Perspectives
    Ajaz F, Haddad J, Huda B et al. · Int J Mol Sci · 2025