Evidence base

Studies on Hyaluronic Acid

Auto-loaded from PubMed — grouped by outcome. Each entry links to the original source.

43,030 studies total·Last updated: June 4, 2026Open on PubMed

Skin · 2,857

Open on PubMed
  1. 01
    Midface volumization and skin quality enhancement with a hyaluronic acid-polynucleotide hybrid filler: a 24-week prospective open-label study
    Lee SY, Youn CS, Park KY · J Dermatolog Treat · 2026
  2. 02
    Exploring the photoprotective and antiaging potential of Padina pavonica loaded Hyatocosomes: In-vitro evaluation and biological studies
    E M Makhlof M, M El-Sheekh M, Abbas H et al. · Bioorg Chem · 2026
  3. 03
    A flexible hydrogel microneedle patch-mediated electrochemical sensor for rapid and minimally invasive fentanyl detection
    Wu T, Huang Q, Luo J et al. · Talanta · 2026
  4. 04
    Enhanced biodistribution and efficacy of nicomenthyl encapsulated in emulsions stabilized by methacrylated hyaluronic acid for the prevention and treatment of skin photoaging
    Zamora P, Moncada Á, Loinaz I et al. · Carbohydr Polym · 2026
  5. 05
    Topical and systemic skin aging interventions: Evidence, pitfalls and perspectives
    Gürtler AL, Sirois JP, Heckenbach IJ et al. · Biochem Pharmacol · 2026
  6. 06
    An electrochemical enzyme-linked immunosorbent assay for interleukin 18 quantification in 3D skin models derived from ALS patients
    Furlan N, D'Amora U, Fasolino I et al. · Biosens Bioelectron · 2026
  7. 07
    GLP-1-Induced Weight Loss and the Face: Anatomical Mechanisms and Rationale for Collagen-Stimulating and Volumizing Aesthetic Treatments
    Frank K, Guertler A, Hoffmeister V et al. · Dermatol Surg · 2026
  8. 08
    Role of HYAL1 on hyaluronan metabolism and the regulation of epidermal tight junction component CLDN1 in HaCaT cells
    Yoshino Y, Genkawa N, Hirose M et al. · Arch Biochem Biophys · 2026
  9. 09
    Investigation into the delivery and evaluation of a unique Avena sativa (Oat) Lipid Extract on skin barrier using LC‒MS/MS, Raman spectroscopy, immunostaining analysis and skin efficacy
    Gombert E, Dewis C · Int J Cosmet Sci · 2026
  10. 10
    Polysaccharide-Based Soluble Microneedle Transdermal Delivery of Curcumin Synergized with Photothermal Therapy for Acne Treatment
    Kannapathirage DMG, Tang S, Ma X et al. · ACS Appl Mater Interfaces · 2026
  11. 11
    A co-amorphous salt of ursodeoxycholic acid and matrine incorporated into dissolving microneedles for combined antibacterial and anti-inflammatory treatment of acne vulgaris
    Zhao Y, Sun Y, Peng J et al. · Int J Pharm · 2026
  12. 12
    Tear Trough Deformity: Update on Anatomy and Clinical Management
    Termanini KM, Alghoul MS · Aesthet Surg J · 2026
  13. 13
    Efficacy and Safety of a Poly-L-Lactic Acid Filler for Temporal Augmentation: A Randomized, No-treatment Control, Evaluator-blinded, Multicenter Study
    Chang G, Tan Z, Ting W et al. · Aesthet Surg J · 2026
  14. 14
    Efficacy of Japanese Maca Powder Against Aging Stress in Human Dermal Fibroblasts
    Dan K, Takanashi K, Kitamura S · Int J Mol Sci · 2026
  15. 15
    Functional hyaluronic acid/gelatin hydrogel accelerates the closure and healing of diabetic wounds
    Du Q, Liu J, Ding C et al. · Carbohydr Polym · 2026
  16. 16
    Valorization of Chum Salmon (Oncorhynchus keta) Processing By-Products: High-Value Functional Food Ingredients for Skin Health
    Kim WC, Lee YS, Jung SR et al. · Mar Drugs · 2026
  17. 17
    Mandelamide Isolated from Prunus persica Flowers Attenuates TNF-α-Driven Oxidative and Inflammatory Responses in Human Skin Cells
    Choi YJ, Ann HW, Son SR et al. · Biomolecules · 2026
  18. 18
    Evaluation of Tissue Response to Coinjection Versus Individual Injection of Hyaluronic Acid Filler and Polycaprolactone Microsphere-Based Filler in a Rabbit Model
    Xie W, Tang Y, Pu C et al. · J Cosmet Dermatol · 2026
  19. 19
    Cross-Linked Sodium Hyaluronate Filler Containing Poly-L-Lactic Acid-b-Poly (Ethylene Glycol) Microspheres for Periorbital Rejuvenation: A Multimodal Assessment of Physicochemical, Preclinical, and Clinical Performance
    Chen W, Lei G, Lou X et al. · J Cosmet Dermatol · 2026
  20. 20
    Multitargeted Modulation of Skin Dullness by HNHT Formulation: Synergistic Inhibition of Melanogenesis, Glycation, and Lipofuscin Deposition
    Wang Z, Fan Y, Ling P · J Cosmet Dermatol · 2026
  21. 21
    Multifunctional Hyaluronic Acid Releasing Hydrogel Film With Nano/Micro Wrinkles: Thin Acne Patch for Localized Therapeutics
    Chowdhury SR, Babu R, Bhadauria P et al. · Macromol Biosci · 2026
  22. 22
    Hyaluronidase Reverses the Effect of Hyaluronic Acid Without Destroying Normal Skin Structure
    Yin B, Jiang Z, Shi J et al. · J Cosmet Dermatol · 2026
  23. 23
    International Expert Consensus on Integrated Skincare Active Ingredients for Pretreatment and Posttreatment Use With Medical Aesthetic Procedures to Enhance Skin Benefits
    Bjerring P, Draelos ZD, Fabi SG et al. · J Cosmet Dermatol · 2026
  24. 24
    Hyaluronic Acid Dermal Filler-Associated Vascular Occlusion-A Review of Prevention and Management Strategies
    Lowe S · J Cosmet Dermatol · 2026
  25. 25
    Fast-dissolving microneedles with tip-loaded ovalbumin for transcutaneous allergen-specific immunotherapy
    Wang Z, Zhu X, Miao Z et al. · Int J Biol Macromol · 2026

Joints · 4,209

Open on PubMed
  1. 01
    Artificial human stem cell niche created in cartilage-inspired hydrogel for enhanced articular cartilage regeneration
    Zhou Z, Hou Y, Yao Z et al. · Biomaterials · 2026
  2. 02
    Ozone injections reduce pain in knee osteoarthritis: a systematic review and meta-analysis
    Arias-Vázquez PI, Castillo-Avila RG, Hernández-Gil K et al. · Med Gas Res · 2026SR
  3. 03
    pH-responsive, self-lubricating hyaluronic acid-chondroitin sulfate-chitosan hydrogel for articular cartilage repair
    Qiu H, Zheng J, Yao Z et al. · Carbohydr Polym · 2026
  4. 04
    Advanced oxidation protein products exacerbate osteoarthritis progression by disrupting stress granules assembly via endoplasmic reticulum stress
    Jiang W, Wang Q, Zhang X et al. · Free Radic Biol Med · 2026
  5. 05
    Lymph nodes-targeted nano-prodrug for precise B cell immunoregulation to prevent collagen-induced arthritis
    Li N, Huang W, Wu Z et al. · Biomaterials · 2026
  6. 06
    Cross-Linked Versus Linear Hyaluronic Acid for Cartilage Repair in Rat Post-Traumatic Osteoarthritis
    Lee TC, Kao CM, Lin YW et al. · J Orthop Res · 2026
  7. 07
    Hyaluronic acid-phosphatidylcholine complexes as reductionist mimics of extracellular vesicle-mediated boundary lubrication in synovial joints
    Zhu L, Seror J, Lin W et al. · Acta Biomater · 2026
  8. 08
    A microscale four-ball tribometer for characterization of lubrication by small volume samples
    Stealey S, Genin GM, Zustiak SP · J Mech Behav Biomed Mater · 2026
  9. 09
    Stiffness-tunable alginate-hyaluronic acid-collagen hydrogel mimics chondrocyte microenvironment for osteoarthritis pathophysiological modeling
    Du G, Wang D, Chen Q et al. · Acta Histochem · 2026
  10. 10
    Biomimetic and microenvironment-adaptive nanoplatform potentiates photodynamic therapy of rheumatoid arthritis via H(2)S-Modulated oxygen metabolism
    Zhang X, Meng S, Xiao Y et al. · Biomaterials · 2026
  11. 11
    Efficacy of ultrasound-guided intra-articular hyaluronic acid injection in the management of adhesive capsulitis: a randomized controlled trial
    Chang CY, Chen CT, Lin YH et al. · J Rehabil Med · 2026RCT
  12. 12
    Injectable gelatin/hyaluronic acid hydrogels incorporating oxidized alginate microparticles for controlled delivery of platelet-derived factors in cartilage regeneration
    Atwal A, Mahnavi A, Snow M et al. · Carbohydr Polym · 2026
  13. 13
    Clinical Features Outperform MRI Radiomics for Predicting Intra-Articular Hyaluronic Acid Response in Knee Osteoarthritis
    Alkhatatbeh T, Alkhatatbeh A, Liao Y et al. · Ann N Y Acad Sci · 2026
  14. 14
    Platelet-rich plasma plus hyaluronic acid vs platelet-rich plasma intra-articular injections for knee osteoarthritis: A systematic review and meta-analysis
    Tomaszewski M, Smereka J, Al-Jeabory M et al. · Adv Clin Exp Med · 2026SR
  15. 15
    Intra-Articular Purified Exosome Product and Hyaluronan Attenuate Osteoarthritis Progression in a Minimally Invasive Turkey Model
    Lei X, Wang L, Reisdorf RL et al. · J Orthop Res · 2026
  16. 16
    Advanced treatment for articular cartilage lesions: Development of an injectable glucosinolate-releasing hyaluronic acid
    Gambari L, Velino C, Gotti R et al. · Int J Biol Macromol · 2026
  17. 17
    Autologous platelet-rich plasma versus hyaluronic acid, corticosteroids or saline for knee osteoarthritis: can blood draw volume serve as a proxy for platelet dose? A systematic review and meta-analysis
    Centeno CJ, Berger DR, Pelle AJ et al. · Int Orthop · 2026SR
  18. 18
    An Injectable Dual-Layer Hydrogel Integrating Adhesive and Bioactive Functions for Cartilage Regeneration
    Atwal A, Dale TP, Snow M et al. · Adv Healthc Mater · 2026
  19. 19
    Diels-Alder Click Chemistry as a Dynamic-Covalent Crosslinking Method in Spheroid-Encapsulating Hydrogels for Cartilage Engineering
    van de Looij SM, Vasilopoulou AG, Spauwen L et al. · Adv Healthc Mater · 2026
  20. 20
    Three-year follow-up from a randomised controlled trial of a single intra-articular polyacrylamide hydrogel injection in subjects with knee osteoarthritis
    Bliddal H, Beier J, Hartkopp A et al. · Clin Exp Rheumatol · 2026RCT
  21. 21
    Intra-articular therapies for synovial joint dysfunction: a comprehensive integrative review
    Neves LBM, Lima BC, Coutinho de Mello R et al. · Oral Surg Oral Med Oral Pathol Oral Radiol · 2026
  22. 22
    Hydrogel-guided p-LOX nanodrug delivery modulates metabolic microenvironment for cartilage repair in osteoarthritis
    Qian Y, Wang S, Sha Y et al. · Biomaterials · 2026
  23. 23
    Temporomandibular joint arthrocentesis complications: A rare arteriovenous fistula
    Val M, Mirko R, Colonna A et al. · Cranio · 2026
  24. 24
    Injectable thermosensitive hydrogels for sustained intra-articular release of TNF-α inhibitors in rheumatoid arthritis
    Miyanroodan SM, Sohail M · Int J Pharm · 2026
  25. 25
    Five-year real-world outcomes of short-course leukocyte-poor PRP versus standard conservative therapy in early-stage knee osteoarthritis
    Yu Q, Wen C, Liu J · PLoS One · 2026