Studienlage

Studien zu L-Glutamin

Automatisch aus PubMed geladen — gruppiert nach Outcome. Jeder Treffer verlinkt direkt zur Originalquelle.

4.545 Studien insgesamt·Stand: 4. Juni 2026Auf PubMed öffnen

Immunsystem · 366

Auf PubMed öffnen
  1. 01
    Transcriptomic profiling reveals T cell-mediated Glutamine immunomodulation via CD8A / LCK / LAT signaling in the liver model of piglets
    Liu G, Cheng Y, Zhang Y et al. · J Nutr Biochem · 2026
  2. 02
    Glutamine alleviates Staphylococcus aureus-induced mastitis by modulating macrophage polarisation
    Feng C, Liu M, He Z et al. · PLoS Pathog · 2026
  3. 03
    Shen Ling Bai Zhu San promotes gut IgA(+) plasma cells to alleviate chronic diarrhea in mice via increasing systematic glutamine
    Chen R, Lin Y, Gao X et al. · J Ethnopharmacol · 2026
  4. 04
    The Glutamine Metabolic Switch Influences the Response of Neonatal Intestinal Macrophages to Breast Milk
    Han X, Hou Y, Chen T et al. · Cell Mol Gastroenterol Hepatol · 2026
  5. 05
    Dietary glutamine supplementation improves growth performance, intestinal morphology, and immunity function associated with cecal microbiota alterations in broilers
    Liu X, Yin S, Fu C et al. · Poult Sci · 2025
  6. 06
    Targeting glutamine catabolism suppresses eosinophil expansion and activation to alleviate allergic airway inflammation
    Du X, Wang Y, Huang J et al. · Biochem Pharmacol · 2025
  7. 07
    Integrative Omics Reveals Glutamine Catabolism-Driven Apoptotic Suppression in Monocytes upon Mechanical Unloading
    Ding Y, Tong F, Liu M et al. · Adv Sci (Weinh) · 2025
  8. 08
    CARMIL2 deficiency disrupts activation-induced metabolic reprogramming in T cells and is partially rescued by glutamine supplementation
    Kabha M, Liaks-Bohnick M, Zagairy F et al. · J Allergy Clin Immunol · 2025
  9. 09
    Glutamine limits NLRP3 inflammasome activation and pyroptosis in macrophages by sustaining the IRG1/itaconate axis
    Chen X, Zhu Y, Xia L et al. · FEBS J · 2025
  10. 10
    Glutamine alleviates immunosuppression in polymicrobial sepsis by augmenting bacterial phagocytosis through sustaining the GFAT-DRP1 dependent mitochondrial calcium dynamics
    Zhu Y, Chen X, Xia L et al. · Clin Sci (Lond) · 2025
  11. 11
    A dendritic cell population responsible for transglutaminase 2-mediated gluten antigen presentation in celiac disease
    Yang FC, Besser HA, Chun HR et al. · JCI Insight · 2025
  12. 12
    Effects of puerarin on growth performance, digestive ability, immune response, and resistance to ammonia stress in Pacific white shrimp (Litopenaeus vannamei) in low-salinity water
    Chang YL, Qi L, Guan CL et al. · Fish Shellfish Immunol · 2025
  13. 13
    Targeting AQP5-mediated arginine deprivation in gastric cancer stem cells restores NK cell anti-tumor immunity
    Zhao R, He B, Huang L et al. · Cell Rep Med · 2025
  14. 14
    Targeting pyruvate metabolism generates distinct CD8+ T cell responses to gammaherpesvirus and B lymphoma
    Kang T, Usherwood YK, Reisz JA et al. · JCI Insight · 2025
  15. 15
    Choline in immunity: a key regulator of immune cell activation and function
    Maia C, Fung CW, Sanchez-Lopez E · Front Immunol · 2025
  16. 16
    Nuclear PHGDH regulates macrophage polarization through transcriptional repression of GLUD1 and GLS2 in breast cancer
    Wang P, Du X, Han Z et al. · Cancer Biol Med · 2025
  17. 17
    Glutamine Administration Attenuates Poly(I:C)-Induced Lung Injury by Reducing Neutrophil Infiltration and Activating the TLR-3 Antiviral Pathway
    Su LH, Tsai WC, Shirakawa H et al. · Nutrients · 2025
  18. 18
    Sex-specific effects of exogenous asparagine on colorectal tumor growth, 17β-estradiol levels, and aromatase
    Aladelokun O, Benitez K, Wang Y et al. · Pharmacol Res · 2025
  19. 19
    Macrophages harness hepatocyte glutamate to boost liver regeneration
    Rigual MDM, Angulo-Aguado M, Zagorac S et al. · Nature · 2025
  20. 20
    Tangeretin modulates gut microbiota metabolism and macrophage immunity following fecal microbiota transplantation in obesity
    Peng W, Jin Z, Liu J et al. · J Food Sci · 2025
  21. 21
    Glutamine Attenuates Inflammation and Stimulates Amniotic Cell Proliferation in Premature Rupture of Membranes-related in vitro Models
    Xiang X, Zhang L, Li S et al. · Reprod Sci · 2025
  22. 22
    Glutamine metabolic competition drives immunosuppressive reprogramming of intratumour GPR109A(+) myeloid cells to promote liver cancer progression
    Yang Y, Pei T, Liu C et al. · Gut · 2025
  23. 23
    ApoE Receptor-2 R952Q Variant in Macrophages Elevates Soluble LRP1 to Potentiate Hyperlipidemia and Accelerate Atherosclerosis in Mice
    Turkson V, Haller A, Jaeschke A et al. · Arterioscler Thromb Vasc Biol · 2025
  24. 24
    Dietary glutamine supplementation improves both Th1 and Th17 responses via CARD11-mTORC1 pathway in murine model of atopic dermatitis
    Fan J, Wang X, Wang Y et al. · Int Immunopharmacol · 2024
  25. 25
    HSP60 controls mitochondrial ATP generation for optimal virus-specific IL-21-producing CD4 and cytotoxic CD8 memory T cell responses
    Ghahari N, Shegefti S, Alaei M et al. · Commun Biol · 2024

Muskelkraft · 207

Auf PubMed öffnen
  1. 01
    Preconditioning and supplementation with glutathione ameliorates oxidative stress, mitochondrial dysfunction, and restores metabolic imbalance in insulin-resistant myotubes
    Save SN, Parveen N, Sonis G et al. · Biochem Biophys Res Commun · 2026
  2. 02
    Glutaminolysis Mediated by the Gut-Muscle Axis Facilitates Collagen Cross-Linking to Regulate Muscle Texture Traits in Tilapia
    Wang Z, Zhu C, Wang Y et al. · J Agric Food Chem · 2026
  3. 03
    Effects of a diet containing glutamine on the slaughter performance, meat quality, and skeletal muscle fiber types of feed-restricted yaks
    Yue Z, Ke S, Shi L et al. · Meat Sci · 2025SR
  4. 04
    Glutamine Promotes Myogenesis in Myoblasts Through Glutaminolysis-Mediated Histone H3 Acetylation That Enhances Myogenin Transcription
    Takatoya M, Kasugai T, Arai D et al. · Nutrients · 2025
  5. 05
    Changes in carcass traits, proximate composition, amino acid profile and inflammatory markers in different muscles of pigs following glutamine supplementation
    Tomaszewska E, Domaradzki P, Świetlicka I et al. · Animal · 2025
  6. 06
    Glutamine Promotes Rotator Cuff Healing by Ameliorating Age-Related Osteoporosis
    Wang H, Cai Z, Ying M et al. · J Bone Joint Surg Am · 2025
  7. 07
    Selected Nutrients to Oppose Muscle Disuse Following Arthroscopic Orthopedic Surgery: A Narrative Review
    Cordingley DM, Taheri M, Fasihiyan M et al. · Nutrients · 2025
  8. 08
    Liver lipid metabolism, oxidative stress, and inflammation in glutamine-supplemented ob/ob mice
    Leite JSM, Vilas-Boas EA, Takahashi HK et al. · J Nutr Biochem · 2025
  9. 09
    Effects of preoperative beta-hydroxy-beta-methylbutyrate, arginine, and glutamine supplementation on cardiac surgery: A randomized controlled trial
    Ogawa M, Satomi-Kobayashi S, Yoshida N et al. · Clin Nutr · 2025RCT
  10. 10
    High leucine bioavailability improves beef quality by altering serum metabolism in beef cattle
    An J, Zhao X, Song Y et al. · Meat Sci · 2025
  11. 11
    Dietary L-glutamine supplementation enhances growth performance and carcass characteristics in Hanwoo heifers via hepatic and skeletal muscle gene regulation
    Jin XC, Park JS, Peng DQ et al. · J Anim Sci · 2025SR
  12. 12
    Dietary protein and amino acid intakes for mitigating sarcopenia in humans
    He W, Connolly ED, Cross HR et al. · Crit Rev Food Sci Nutr · 2025
  13. 13
    The effect of Sarcomeal® oral supplementation plus vitamin D3 on muscle parameters and metabolic factors in diabetic sarcopenia patients: study protocol of a randomized controlled clinical trial
    Abdi Dezfouli R, Zargar Balajam N, Shirazi S et al. · Trials · 2024
  14. 14
    Vitamin D administration increases serum alanine concentrations in thermally injured mice
    Sato Y, Hishiki T, Masugi Y et al. · Biochem Biophys Res Commun · 2024
  15. 15
    A systematic review to assess the impact of amino acids or their derivatives on skeletal muscle wasting in critically ill patients
    Wittholz K, Bidgood E, Fetterplace K et al. · Clin Nutr · 2024SR
  16. 16
    Effects of essential amino acid (EAA) and glutamine supplementation on skeletal muscle wasting in acute, subacute, and postacute conditions
    Negro M, Crisafulli O, D'Antona G · Clin Nutr ESPEN · 2024
  17. 17
    Perioperative Glutamine Supplementation May Restore Atrophy of Psoas Muscles in Gastric Adenocarcinoma Patients Undergoing Gastrectomy
    Wu JM, Tsai HH, Tseng SM et al. · Nutrients · 2024
  18. 18
    Novel peptides from sea cucumber intestines hydrolyzed by neutral protease alleviate exercise-induced fatigue via upregulating the glutaminemediated Ca(2+) /Calcineurin signaling pathway in mice
    Lu X, Wang M, Yue H et al. · J Food Sci · 2024
  19. 19
    Oral glutamine supplementation relieves muscle loss in immobilized rats, altering p38MAPK and FOXO3a signaling pathways
    Petry ÉR, Dresch DF, Carvalho C et al. · Nutrition · 2024
  20. 20
    Changes in Skeletal Muscle Protein Metabolism Signaling Induced by Glutamine Supplementation and Exercise
    Rodrigues Junior CF, Murata GM, Gerlinger-Romero F et al. · Nutrients · 2023
  21. 21
    Blockade of glucagon increases muscle mass and alters fiber type composition in mice deficient in proglucagon-derived peptides
    Ueno S, Seino Y, Hidaka S et al. · J Diabetes Investig · 2023
  22. 22
    Glutamine supplementation accelerates functional recovery of EDL muscles after injury by modulating the expression of S100 calcium-binding proteins
    Santos AR, Koike TE, Santana AM et al. · Histochem Cell Biol · 2023
  23. 23
    Influence of Mechanistic Target of Rapamycin (mTOR)-Regulated Anabolic Pathways on Equine Skeletal Muscle Health
    Semanchik PL, Wesolowski LT, Ryan PJ et al. · J Equine Vet Sci · 2023
  24. 24
    Identification and Quantification of Proliferating Cells in Skeletal Muscle of Glutamine Supplemented Low- and Normal-Birth-Weight Piglets
    Albrecht E, Zhao Y, Sciascia QL et al. · Cells · 2023
  25. 25
    Acute heat stress-indued apoptosis in mouse skeletal muscle is not associated with alteration of glutamine homeostasis
    Chen Y, Yu T, Deuster PA · PLoS One · 2022

Stoffwechsel · 170

Auf PubMed öffnen
  1. 01
    Preconditioning and supplementation with glutathione ameliorates oxidative stress, mitochondrial dysfunction, and restores metabolic imbalance in insulin-resistant myotubes
    Save SN, Parveen N, Sonis G et al. · Biochem Biophys Res Commun · 2026
  2. 02
    Capparis Spinosa and Glutamine Reduce Oxidative Stress via Nrf2/Ho-1 Pathway in Diabetic Wound Healing
    Ercan BC, Gursoy EN, Kaltalioglu K et al. · Chem Biodivers · 2026
  3. 03
    Lacto-N-triose II alleviates metabolic dysfunction-associated Steatotic liver disease via microbiota-dependent citrulline biosynthesis
    Chen K, Yu H, Liu B et al. · Food Res Int · 2026
  4. 04
    Circulating amino acids and Type 2 diabetes in a Latin American population-based cohort
    Huidobro L, Cofre S, Santos JL et al. · Cardiovasc Diabetol · 2026
  5. 05
    The Association Between Amino Acids and the Onset and Progression of Type 2 Diabetes Mellitus: A Comprehensive Analysis Based on UK Biobank Database
    Yang J, Wu Z, Fang J et al. · J Diabetes Res · 2026
  6. 06
    Preparation and characterization of glutamine/chito-oligosaccharide modified zein nanoparticles: Controlled release naringin and anti-diabetes
    Guo Y, Xu M, Chen J et al. · Food Chem · 2025
  7. 07
    Combined supplementation of leucine and glutamine acts as a novel therapeutic approach to alleviate hyperglycemia and oxidative stress by targeting insulin signalling genes in a drosophila model of type 2 diabetes
    Dash K, Mishra M · Mol Biol Rep · 2025
  8. 08
    Alpha-ketoglutarate mitigates insulin resistance and metabolic inflexibility in a mouse model of Ataxia-Telangiectasia
    Sun JK, Hart RP, Herrup K et al. · Nat Commun · 2025
  9. 09
    Metabolomics in cardiometabolic diseases: Key biomarkers and therapeutic implications for insulin resistance and diabetes
    Rizo-Roca D, Henderson JD, Zierath JR · J Intern Med · 2025
  10. 10
    Liver lipid metabolism, oxidative stress, and inflammation in glutamine-supplemented ob/ob mice
    Leite JSM, Vilas-Boas EA, Takahashi HK et al. · J Nutr Biochem · 2025
  11. 11
    The effect of Sarcomeal® oral supplementation plus vitamin D3 on muscle parameters and metabolic factors in diabetic sarcopenia patients: study protocol of a randomized controlled clinical trial
    Abdi Dezfouli R, Zargar Balajam N, Shirazi S et al. · Trials · 2024
  12. 12
    Prevotella copri alleviates hyperglycemia and regulates gut microbiota and metabolic profiles in mice
    Yang C, Lan R, Zhao L et al. · mSystems · 2024
  13. 13
    Reduced adipocyte glutaminase activity promotes energy expenditure and metabolic health
    Lecoutre S, Maqdasy S, Rizo-Roca D et al. · Nat Metab · 2024
  14. 14
    Theabrownin from Fu Brick tea ameliorates high-fat induced insulin resistance, hepatic steatosis, and inflammation in mice by altering the composition and metabolites of gut microbiota
    Lu Z, Zheng Y, Zheng J et al. · Food Funct · 2024
  15. 15
    Plant-based diets, mediating biomarkers, and mortality risk among adults with diabetes or prediabetes
    Tao HW, Han WW, Fang F et al. · Food Funct · 2024
  16. 16
    Maternal glycemic status during pregnancy and mid-childhood plasma amino acid profiles: findings from a multi-ethnic Asian birth cohort
    Liu M, Chan SY, Eriksson JG et al. · BMC Med · 2023
  17. 17
    Dietary Glutamine and Glutamate in Relation to Cardiovascular Disease Incidence and Mortality in the United States Men and Women with Diabetes Mellitus
    Chen Z, Hu Y, Hu FB et al. · J Nutr · 2023
  18. 18
    Dietary supplementation with L-leucine reduces nitric oxide synthesis by endothelial cells of rats
    Tekwe CD, Luan Y, Meininger CJ et al. · Exp Biol Med (Maywood) · 2023
  19. 19
    Deficiency of the metabolic enzyme SCHAD in pancreatic β-cells promotes amino acid-sensitive hypoglycemia
    St-Louis JL, El Jellas K, Velasco K et al. · J Biol Chem · 2023
  20. 20
    Optimizing glycation control in diabetes: An integrated approach for inhibiting nonenzymatic glycation reactions of biological macromolecules
    Song H, Ma H, Shi J et al. · Int J Biol Macromol · 2023
  21. 21
    Effects on Diabetic Mice of Consuming Lipid Extracted from Foxtail Millet (Setaria italica): Gut Microbiota Analysis and Serum Metabolomics
    Wang H, Shen Q, Fu Y et al. · J Agric Food Chem · 2023
  22. 22
    An early, reversible cholesterolgenic etiology of diet-induced insulin resistance
    Covert JD, Grice BA, Thornburg MG et al. · Mol Metab · 2023
  23. 23
    Pancreatic β-cell glutaminase 2 maintains glucose homeostasis under the condition of hyperglycaemia
    Deguchi-Horiuchi H, Suzuki S, Lee EY et al. · Sci Rep · 2023
  24. 24
    Metabolic Homeostasis of Amino Acids and Diabetic Kidney Disease
    Liu L, Xu J, Zhang Z et al. · Nutrients · 2022
  25. 25
    Effects of a Short-Term Meal Replacement Hypocaloric Diet in Subjects with Obesity and High Fatty Liver Index
    Luis D, Primo D, Izaola O et al. · Nutrients · 2022