Studienlage

Studien zu Testosteronersatztherapie (TRT)

Automatisch aus PubMed geladen — gruppiert nach Outcome. Jeder Treffer verlinkt direkt zur Originalquelle.

17.872 Studien insgesamt·Stand: 4. Juni 2026Auf PubMed öffnen

Hormonbalance · 9.897

Auf PubMed öffnen
  1. 01
    Testosterone deficiency in aging males: a dual threat to vascular and bone health through coronary artery calcification and osteoporosis - a narrative review
    Li S · Aging Male · 2026
  2. 02
    Testosterone replacement therapy in older men: skeletal outcomes and fracture risk
    Szarpak L, Al-Jeabory M, Pecold J et al. · Aging Male · 2026
  3. 03
    Association between COVID-19 status and Leydig cell functional capacity among men in hospitalized cohorts
    Anand-Ivell R, Yang X, Tarr AW et al. · Aging Male · 2026
  4. 04
    Association between chronic inflammation status and serum testosterone and free testosterone in adult males
    Zhang SZ, Meng YH, Qi SD et al. · Aging Male · 2026
  5. 05
    Vitamin D levels in relation to sexual steroids, sexual function, and quality of life in patients of an andrology outpatient clinic
    Haider KS, Zitzmann M · Aging Male · 2026
  6. 06
    Preoperative Testosterone Replacement Therapy Is Associated With Increased Complication Risk After Total Knee Arthroplasty: A Propensity-Matched Analysis of 13,250 Patients
    Omurzakov A, Omurzakov AM, Bhatti P et al. · J Arthroplasty · 2026
  7. 07
    Gonadotropin-releasing hormone receptor mutation as a cause of pubertal delay
    Lucas M, da Bernarda Rodrigues I, Rosmaninho-Salgado J et al. · BMJ Case Rep · 2026
  8. 08
    Efficacy of Testosterone Replacement Therapy Combined With Exercise on Body Composition in Hypogonadal Men
    Shigehara K, Shinzawa R, Sakatoku N et al. · Int J Urol · 2026
  9. 09
    Effect of testosterone replacement therapy on fracture risk in hypogonadal men: A systematic review and meta-analysis of randomized controlled trials
    Anagnostis P, Divaris E, Zidrou M et al. · Maturitas · 2026SR
  10. 10
    Caring for Gender Diverse Youth With Duchenne Muscular Dystrophy: A Multisite Case Series
    Melendez Garcia CE, Ahmed UA, Pagan A et al. · Pediatr Neurol · 2026
  11. 11
    Obesity inhibits hypothalamic activation and luteinizing hormone dynamics through Sox-2-dependent demyelination
    Nie Y, Guo W, Qiu L et al. · Neurobiol Dis · 2026
  12. 12
    Effects of testosterone undecanoate as add-on therapy in obese hypogonadal men that are late responders to tirzepatide: a pilot study
    Seminara G, Leuzzi M, Meduri L et al. · Minerva Endocrinol (Torino) · 2026
  13. 13
    Low Testosterone Levels and Grade Group Progression Among Localized Prostate Cancer Patients on Active Surveillance: A Retrospective Cohort Study
    Lawen T, Garcia RS, Smith MT et al. · J Urol · 2026
  14. 14
    Testosterone Does Not Drive Prostate Cancer: Presenting the New Framework of Androgen Adequacy vs Inadequacy
    Morgentaler A, Traish AM · J Urol · 2026
  15. 15
    Fractionated testosterone gel replacement therapy in clinical practice: A real-world exploratory clinical experience
    Maltese V, Delbarba A, Gatta E et al. · Endocrine · 2026
  16. 16
    A Rare Coexistence of Turner Syndrome and Mycosis Fungoides: A Case Report
    Bayrak Demirel O, Karakilic-Ozturan E, Atci T et al. · J Clin Res Pediatr Endocrinol · 2026
  17. 17
    Microglia Rank signaling regulates GnRH neuronal function and the hypothalamic-pituitary-gonadal axis
    Collado-Sole A, Borjini N, Zhai J et al. · Science · 2026
  18. 18
    Discordance Between Online Information and Male Hypogonadism Clinical Guidelines: A Global Multilingual Content Analysis
    Grant B, de Silva NL, Gumssani M et al. · J Clin Endocrinol Metab · 2026
  19. 19
    Testosterone and Bone Health in Men
    Kafel H, Basaria S · Curr Osteoporos Rep · 2026
  20. 20
    High triglyceride-glucose index and changes in triglyceride-glucose index are associated with an increased risk of hypogonadism in middle-aged Taiwanese men: a retrospective longitudinal study
    Liao CC, Hung CL, Lee JD et al. · Front Endocrinol (Lausanne) · 2026
  21. 21
    Relationship of erithrocyte membrane polyunsaturated fatty acid composition with biochemical hypogonadism in aging male: evidence from a cross-sectional analysis
    Ucar T, Khan S, Kadioglu A · World J Urol · 2026
  22. 22
    Risk of complications after total hip arthroplasty in patients on testosterone replacement therapy
    Khury F, Antonioli S, Ruff G et al. · Eur J Orthop Surg Traumatol · 2026
  23. 23
    Testosterone protects from metabolic syndrome-associated lung dysfunction in a high-fat diet rabbit model
    Guarnieri G, Comeglio P, Filippi S et al. · Endocrinology · 2026
  24. 24
    Clinical and Genetic Profile of Gordon-Holmes Syndrome: A Review of Published Cases : Original Article
    Mahale RR, Mailankody P · Cerebellum · 2026
  25. 25
    Incidence and risk factors of low testosterone in infertile men with normal sperm concentration
    Lin CW, Huang EY, Huang WJ et al. · Front Endocrinol (Lausanne) · 2026

Muskelkraft · 213

Auf PubMed öffnen
  1. 01
    Endocrinological aspects of sarcopenic obesity
    Minnetti M, Poggiogalle E, Frigerio F et al. · Ann Med · 2026
  2. 02
    Anabolic resistance in cancer cachexia: a role for sex and chemotherapy
    Jenkins T, Zhang Q, Carson JA · Curr Opin Clin Nutr Metab Care · 2026
  3. 03
    Age-Dependent Muscular Response to Testosterone-Based Gender-Affirming Therapy: Evidence From a 1-Year Observational Study
    Ceolin C, Savino S, Gregorio C et al. · Endocr Pract · 2026
  4. 04
    Myostatin in the pituitary-muscle axis: Roles in health and disease
    Iglesias P · Endocrinol Diabetes Nutr (Engl Ed) · 2026
  5. 05
    Testosterone plus lifestyle therapy improves skeletal muscle glycolysis in older men with obesity and hypogonadism
    Viola V, Aguilar M, Nava MLD et al. · Front Endocrinol (Lausanne) · 2025RCT
  6. 06
    Androgen deprivation induces distinct muscle-specific transcriptional changes to genes regulating glucose, lipid, and amino acid metabolism
    Ayers-Creech WA, Steiner JL, Laskin GR et al. · Mol Cell Endocrinol · 2026
  7. 07
    Sustained Accumulation of Molecular Clock Suppressors Period 1 and Period 2 Promotes C2C12 Myotube Atrophy Through an Autocrine-Mediated Mechanism With Relevance to Androgen Deprivation-Induced Limb Muscle Mass Loss
    Laskin GR, Steiner JL, Ayers-Creech WA et al. · Function (Oxf) · 2025
  8. 08
    Testosterone Modulation of Muscle Transcriptomic Profile During Lifestyle Therapy in Older Men with Obesity and Hypogonadism
    Viola V, Samanta T, Nava MLD et al. · J Cachexia Sarcopenia Muscle · 2025RCT
  9. 09
    Castration Levels of Testosterone Results in Atrophy of Androgen-sensitive Perineal Muscles: A Potential Biomarker for Male Hypogonadism
    Rathi N, Blake Z, Hyman J et al. · Urology · 2025
  10. 10
    Insulin resistance during androgen deprivation therapy in men with prostate cancer
    Basaria S, Taplin ME, McDonnell M et al. · Cancer · 2024
  11. 11
    Use of testosterone replacement therapy in the rehabilitation of patients with intensive care unit-associated weakness and hospital-associated deconditioning: the Singapore General Hospital rehabilitation experience
    Samuel GS, Swee DS · Singapore Med J · 2024
  12. 12
    Temporal and masseter muscle evaluation by MRI provides information on muscle mass and quality in acromegaly patients
    Gatto F, Milioto A, Corica G et al. · Pituitary · 2024
  13. 13
    Creatinine and Cystatin C: A Measure of Renal Function in Men With Testosterone-Induced Muscle Hypertrophy
    Ashouri R, Lertkitcharoenpon A, Maidaa M et al. · Am J Mens Health · 2024
  14. 14
    Beneficial effects of exercise, testosterone, vitamin D, calcium and protein in older men-A randomized clinical trial
    Midttun M, Overgaard K, Zerahn B et al. · J Cachexia Sarcopenia Muscle · 2024RCT
  15. 15
    Nonalcoholic Fatty Liver Disease, Bone and Muscle Quality in Prolactinoma: A Pilot Study
    Eroğlu İ, Iremli BG, Erkoc A et al. · J Clin Densitom · 2024
  16. 16
    Hypogonadism is frequent in very old men with multimorbidity and is associated with anemia and sarcopenia
    Schluessel S, Bidlingmaier M, Martini S et al. · Z Gerontol Geriatr · 2024
  17. 17
    CORR Insights®: Testosterone Therapy Is Associated With Increased Odds of Quadriceps Tendon Injury
    Owusu-Akyaw K · Clin Orthop Relat Res · 2024
  18. 18
    Testosterone Therapy Is Associated With Increased Odds of Quadriceps Tendon Injury
    Meghani O, Albright JA, Testa EJ et al. · Clin Orthop Relat Res · 2024
  19. 19
    Current and investigational medications for the treatment of sarcopenia
    Rolland Y, Dray C, Vellas B et al. · Metabolism · 2023
  20. 20
    SIRT1 induction in the skeletal muscle of male mice partially attenuates changes to whole-body metabolism in response to androgen deprivation
    Laskin GR, Steiner JL, Berryman CE et al. · Biochem Biophys Res Commun · 2023
  21. 21
    SIRT1 induction in the skeletal muscle of male mice partially preserves limb muscle mass but not contractile force in response to androgen deprivation
    Gordon BS, Burns PK, Laskin GR et al. · J Physiol · 2023
  22. 22
    Safety and Efficacy of Testosterone Therapy on Musculoskeletal Health and Clinical Outcomes in Men: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials
    Buratto J, Kirk B, Phu S et al. · Endocr Pract · 2023Meta
  23. 23
    The Relationship Between Testosterone Therapy and Rotator Cuff Tears, Repairs, and Revision Repairs
    Testa EJ, Albright JA, Hartnett D et al. · J Am Acad Orthop Surg · 2023
  24. 24
    Effects of Testosterone Replacement Therapy on Muscle Strength in Older Men with Low to Low-Normal Testosterone Levels: A Systematic Review and Meta-Analysis
    Lee TW, Kao PY, Chen YC et al. · Gerontology · 2023Meta
  25. 25
    Testosterone Therapy for Dropped Head Syndrome: A Case Report
    Felong TJ, Balos LL, Silvestri NJ · J Clin Neuromuscul Dis · 2022

Longevity & Aging · 745

Auf PubMed öffnen
  1. 01
    Testosterone deficiency in aging males: a dual threat to vascular and bone health through coronary artery calcification and osteoporosis - a narrative review
    Li S · Aging Male · 2026
  2. 02
    Endocrinological aspects of sarcopenic obesity
    Minnetti M, Poggiogalle E, Frigerio F et al. · Ann Med · 2026
  3. 03
    Testosterone and Bone Health in Men
    Kafel H, Basaria S · Curr Osteoporos Rep · 2026
  4. 04
    Relationship of erithrocyte membrane polyunsaturated fatty acid composition with biochemical hypogonadism in aging male: evidence from a cross-sectional analysis
    Ucar T, Khan S, Kadioglu A · World J Urol · 2026
  5. 05
    From "Passive Supplementation" to "Active Repair": Melatonin Reshapes the Treatment Paradigm for Late-Onset Hypogonadism by Targeting Leydig Cell Senescence
    Wu H, Ning G, Jian M et al. · Aging Cell · 2026
  6. 06
    NGF administration is associated with increased GnRH immunoreactivity and a GnRH-associated phenotype in hypothalamic NSCs of aging mice
    Luo J, Jiang J, Zhang T et al. · Front Endocrinol (Lausanne) · 2026
  7. 07
    Will Selective Androgen Receptor Modulators Ever Reach The Clinic?
    Dias JP, Dobs AS · J Clin Endocrinol Metab · 2026
  8. 08
    Endothelial Sirtuins and Mitochondrial Function Are Associated With Testosterone Status: Implications for Accelerated Vascular Aging in Middle-Age and Older Men With Low Testosterone
    Nguyen BL, Kehmeier MN, Babcock MC et al. · Aging Cell · 2026
  9. 09
    Functional testosterone deficiency in aging men: Clinical impact, diagnostic pathways, and treatment strategies
    Zitzmann M, Soave A, Bier S · Maturitas · 2026
  10. 10
    Gonadotropins Across the Lifespan: Their role in the Neurodevelopment-Neurodegeneration Continuum
    Galbraith JA, Elhassan MZ, Rocha JF et al. · Yale J Biol Med · 2026
  11. 11
    Targeting the CMKLR1-Mediated Signaling Rebalances Immunometabolism State in Middle-Age Testicular Macrophages
    Zhu Z, Du F, Liu Y et al. · Adv Sci (Weinh) · 2026
  12. 12
    "Still a man": exploring the psychosocial experience of sexual aging and identity among older men with hypogonadism
    Badawy W, Shaban M · Aging Ment Health · 2026
  13. 13
    Serum Minerals and Male Age-related Hypogonadism: Multimodal Evidence Decoding Associations and Intervention Strategies
    Xie J, Wang C, Yao J et al. · J Clin Endocrinol Metab · 2026
  14. 14
    Age-Stratified Reference Ranges for Directly Measured Serum Free Testosterone in Community-Dwelling and Healthy Men
    Walravens J, Snaterse G, Narinx N et al. · J Clin Endocrinol Metab · 2026
  15. 15
    When Testosterone Fades: Leydig Cell Aging Shaped by Environmental Toxicants, Metabolic Dysfunction, and Testicular Niche Crosstalk
    Kaltsas A, Dimitriadis F, Zachariou A et al. · Cells · 2026
  16. 16
    Lipid Droplet-Driven Ribosome Collisions Trigger ZAKα-p38 Signaling to Accelerate Testicular Aging
    Xu Y, Shi X, Yin Y et al. · Aging Cell · 2026
  17. 17
    Efficacy and Safety of Clomiphene Citrate for Late-Onset Hypogonadism as Evaluated by Aging Male Symptom Rating Scale Over One Year
    Anno Y, Tsujimura A, Kasai R et al. · Int J Urol · 2026
  18. 18
    Monotropein improves late-onset hypogonadism in TM3 Leydig cells and aged rats
    Kwon HY, Lee H, Choi JS et al. · Biomed Pharmacother · 2025
  19. 19
    Recommendations for diagnosis and treatment of the aging male with Klinefelter syndrome
    Zitzmann M, Sansone A, Jannini EA et al. · Aging Male · 2025
  20. 20
    PRDX1 promotes testosterone synthesis and attenuates aging via redox regulation of ATG4B to modulate lipophagy
    Zhang H, Ma K, Zhuang Y et al. · Nat Commun · 2025
  21. 21
    Testosterone and Obesity in an Aging Society
    Tsutsumi T, Tsuchiya K · Biomolecules · 2025
  22. 22
    Distinct patterns of hypogonadism in a cross-sectional study of Malaysian men with type 2 diabetes mellitus: The role of insulin resistance, visceral adiposity, and aging
    Kang WH, Sukor N, Kamaruddin NA · J Diabetes Investig · 2025
  23. 23
    Epigenetic age acceleration in Turner and Klinefelter syndrome: Correlations with clinical aging markers
    Hasselholm EB, Just J, Chang S et al. · Clin Epigenetics · 2025
  24. 24
    The role and mechanism of quercetin in improving late-onset hypogonadism through network analysis and experimental validation
    Wu X, Zhao H, Huang X et al. · Naunyn Schmiedebergs Arch Pharmacol · 2025
  25. 25
    Mechanisms of Leydig Cell Aging and Obesity-Related Hypogonadism in Men: A Review
    Huang X, Zhao H, Wu X et al. · Med Sci Monit · 2025