OtherStrong evidence

Minoxidil

The second mainstay against hair loss — a topically applied vasodilator. Over-the-counter and effective, but it's a lifelong commitment: stop, and the loss returns.

Also known as: minoxidil, regaine, rogaine

How it works

Minoxidil widens blood vessels and prolongs the growth phase (anagen) of hair follicles, so more and thicker hairs regrow. The exact mechanism isn't fully understood, but the effect is well documented. As with finasteride, the benefit lasts only with continued use.

Goals
Hair
Timing
Any time
Price tier
Low

Dosage

Topical (5%) as solution or foam, 1–2×/day. Effect only with continued use. Low-dose oral minoxidil is increasingly used off-label — that form is prescription only.

Considerations

Topical minoxidil is well supported and available over the counter. Early on there's often a temporary 'shedding' phase (increased shedding) before new growth begins. It's a medication, not a supplement — and only works as long as you keep using it. Oral minoxidil belongs in a physician's hands.

VeganNot during pregnancy
Form
Liquid

Scientific detail

Mechanisms
Vasodilation at the hair folliclePotassium-channel openerProlongs the growth (anagen) phase
Evidence base

Studies on Minoxidil

2,956 studies total · Open on PubMed

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Articles on Minoxidil

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