Nicotinamide Riboside (NR)
An NAD⁺ precursor and direct competitor to NMN. Both demonstrably raise NAD⁺ levels in humans — whether that translates into measurably healthier aging is still open.
How it works
Nicotinamide riboside is a precursor of NAD+, which declines with age and is needed for energy metabolism, DNA repair and sirtuin activity. NR demonstrably raises blood NAD+ levels. Whether that translates into tangible anti-aging effects in humans is not yet established.
Dosage
Studies mostly use 250–500 mg/day. The best-known branded form of NR is 'Niagen'.
Considerations
NR vs. NMN: both reliably raise blood NAD⁺ in humans (well established). The next step — measurable healthspan or lifespan benefits in healthy people — remains preliminary. Choosing between NR and NMN is more a question of price and brand than of proven superiority (see NMN).



