Topic cluster

Cognition

Mental sharpness is negotiable — especially with age. Creatine for the brain, sleep as a reset button, epigenetic levers against cognitive decline.

15 articles · 3 compounds in the database
Subtopics
Creatine (8)Cognition (5)Sleep (5)Epigenetics (1)
Articles
Wheat germ, aged cheese and mushrooms on a dark matte surface — dietary sources of the polyamine spermidine
Supplements

Spermidine: Autophagy Hype vs. the Evidence

Nils GregersenNils GregersenFounder & author · Longevity enthusiast
5 min
Cup of black filter coffee on a dark table next to coffee beans — coffee as a longevity food.
Nutrition

Coffee & Caffeine: How Much Is Healthy — and When It Hurts

Nils GregersenNils GregersenFounder & author · Longevity enthusiast
3 min
Fit person in their late 40s doing a controlled strength move in a dark studio — strength and healthy aging.
Supplements

Creatine for Brain, Bone & Longevity — Beyond Muscle

Nils GregersenNils GregersenFounder & author · Longevity enthusiast
4 min
A scoop of white creatine monohydrate powder on a dark surface next to a faint molecular structure.
Supplements

Creatine: The 5 Biggest Myths — and What the Science Says

Nils GregersenNils GregersenFounder & author · Longevity enthusiast
4 min
Nils in a bright kitchen behind his longevity stack — omega-3, vitamin D3+K2, magnesium, CoQ10 and NMN
Supplements

My Longevity Supplements: The Winners in My Stack

Nils GregersenNils GregersenFounder & author · Longevity enthusiast
4 min
Person in the dark, face lit by screen light, abstract stimulus streams — digital overstimulation and dopamine.
Cognition

Digital Overstimulation & the Dopamine Myth

Nils GregersenNils GregersenFounder & author · Longevity enthusiast
3 min
Person at night in front of a glowing monitor in a dark room — gaming, sleep and sedentary time.
Cognition

Gaming & Longevity: When Playing Harms Your Health — and When It Doesn't

Nils GregersenNils GregersenFounder & author · Longevity enthusiast
4 min
Still life of nutrient-dense whole foods — eggs, sardines, liver, berries, leafy greens
Nutrition

Nutrient Density vs. Adequacy: Why Nutrition Science Needs More Humility

Nils GregersenNils GregersenFounder & author · Longevity enthusiast
6 min
A fit man in his early 60s in a bright kitchen behind a curated row of longevity supplements (D3+K2, magnesium, omega-3, creatine, CoQ10, green tea)
Supplements

Longevity Supplements: The Honest List — What's Proven and What's Overhyped

Nils GregersenNils GregersenFounder & author · Longevity enthusiast
3 min
Two athletes celebrating a win at a world championship — success built on consistent systems
Mindset & Behavior

The Motivation Trap: Why Systems and Habits Change You – Not Motivation

Nils GregersenNils GregersenFounder & author · Longevity enthusiast
4 min
Pills, syringes, and vials — the pharmacological toolkit of modern biohacking
Biohacking

Biohacking, TRT & GLP-1: Where Optimization Makes Sense — and Where It Tips into Risk

Nils GregersenNils GregersenFounder & author · Longevity enthusiast
6 min
Brain visualization with sugar symbolism — insulin resistance accelerates brain aging
Metabolism

Keto, Insulin Resistance and the Aging Brain: Why Ketones Are the 'Clean' Fuel

Nils GregersenNils GregersenFounder & author · Longevity enthusiast
5 min
Person sleeping in bed — restful sleep as the foundation of cellular recovery
Sleep

Sleep Science: Chronotypes, Melatonin Myths and the Nightly Reset

Nils GregersenNils GregersenFounder & author · Longevity enthusiast
5 min
Person surrounded by everyday chemical icons — symbol of daily toxin exposure
Performance & toxins

Peak Span: How Visceral Fat, BPA and Lifestyle Steal Our Best Years

Nils GregersenNils GregersenFounder & author · Longevity enthusiast
3 min
Visualization of the biological clock — aging as a programmable process
Epigenetics & Age Reversal

Aging as a Curable Disease: Can We Reverse the Biological Clock?

Nils GregersenNils GregersenFounder & author · Longevity enthusiast
4 min
Compounds & substances
AdaptogenModerate

Rhodiola Rosea

Adaptogen from arctic regions. Active compounds rosavin and salidroside modulate the HPA axis and support stress resilience, mental performance, and fatigue reduction. Effects are typically noticeable within hours.

Dose200–600 mg/day of standardised extract (3 % rosavin, 1 % salidroside). Morning on empty stomach. Cycle — e.g. 6 weeks on, 2 weeks off.
· Morning
AdaptogenModerate

Ashwagandha (KSM-66)

Adaptogen with solid RCT evidence for cortisol reduction, sleep quality, and perceived stress.

Dose300–600 mg KSM-66 per day, preferably in the evening.
· Evening
EssentialStrong

Creatine Monohydrate

One of the most thoroughly studied supplements. Benefits for muscle, bone, and increasingly cognition.

Dose3–5 g/day, any time. No loading phase needed.
· Any time